| abstract |
The invention relates to the use of a compound of formula (I), wherein X is H, OH, Cl, F or a methyl group and Y is Cl, OH, -(CH2)2-N(CH3)-(CH2)4-CH3, -(CH2)n-CH3 or -(CH2)n-NH2, where n is zero or an integer of 1 to 8, -NHZ, where Z is pyridinyl or cycloheptyl, -SZ', where Z' is pyridinyl or chloro-substituted phenyl, or Y is a pyridinylsubstituted lower alkyl chain; or a non-toxic, pharmaceutically acceptable salt or ester thereof for the manufacture of a pharmaceutical composition to be used in enhancing the formation of bone tissue and/or eliminating late complications subsequent to bone surgery in a bone surgery patient before and/or after said surgery. |