| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea7da26cb077e35d67c7703ba5e49d7d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F23-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-413 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F23-4105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-671
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-0245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F23-482
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F23-511
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N25-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N57-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F3-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F3-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate |
1994-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af49614e9c82738ec1e10f8a25a51445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e351eaf20dd6dca426b82c4a708569f9 |
| publicationDate |
2002-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0687172-B1 |
| titleOfInvention |
Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
| abstract |
The present invention is in the area of administration forms and delivery systems for drugs, vaccines and other biologically active agents. More specifically the invention is related to the preparation of suspensions of colloidal solid lipid particles (SLPs) of predominantly anisometrical shape with the lipid matrix being in a stable polymorphic modification and of suspensions of micron and submicron particles of bioactive agent (PBAs); as well as to the use of such suspensions or the lyophilizates thereof as delivery systems primarily for the parenteral administration of preferably poorly water-soluble bioactive substances, particularly drugs, and to their use in cosmetic, food and agricultural products. The emulsification process includes melting of the agent (a lipid and for bioactive agent) and mixing with an aqueous phase (heated to melt temperature). The emulsification is completed by a high-pressure homogenization. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7939106-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8206746-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7943666-B2 |
| priorityDate |
1993-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |