| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate |
1995-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf3d1684bca05831b55574465be2d7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ada713cfa950315adee6238da51aa935 |
| publicationDate |
1997-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0685487-B1 |
| titleOfInvention |
A new method of preparation of a 16-beta-steroid and new intermediates of said preparation |
| abstract |
Prodn. of 16 beta -methyl-17 alpha -hydroxy- 4,9(11)-pregnadiene-3,20-dione of formula (I) comprises: (a) treating a 17 alpha -hydroxy-17 beta -nitrile with a dehydrating agent to give a 16,17-dehydro-17-nitrile; (b) protecting the oxo gp. if necessary; (c) reacting with an organometallic methylating agent and hydrolysing the resulting imine to give a methyl ketone; (d) treating with an epoxidising agent in a basic medium to give a 16 alpha ,17 alpha -epoxide; (e) protecting the 20-oxo gp.; (f) reacting with an organometallic methylating agent to give a 16 beta -methyl deriv.; and (g) deprotecting the oxo gps. to give (I). |
| priorityDate |
1994-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |