| abstract |
A pyrimidine derivative represented by general formula (I) or a salt thereof, having an angiotensin II antagonism. In said formula, A represents (I-1) or (I-2), R¹ and R² represent each independently hydrogen, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, acetyl, halogen, phenyl or substituted phenyl; R³ represents hydrogen, alkyl, alkenyl, alkynyl or acetyl; X represents O, MH or S(O)p; p represents an integer of 0 to 2; m represents an integer of 1 or 2; B represents carboxy, alkoxycarbonyl, cyano, tetrazolyl or protected tetrazolyl; and n represents an integer of 1 to 2. |