http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0684954-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1ebf89b1ed6362db9fc10ab0a3206de |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 1994-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6e75160fd3819c277bffdcac4e1e09c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f20d3b8a7f442ab348cb362bf514371b |
| publicationDate | 1995-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0684954-A1 |
| titleOfInvention | Nucleic acid probes chemically 5'(oh)- and/or 3'(oh)-modified for inserting one or more non-radioactive labeling elements thereat, and method for preparing same |
| abstract | PCT No. PCT/BE94/00013 Sec. 371 Date Aug. 21, 1995 Sec. 102(e) Date Aug. 21, 1995 PCT Filed Feb. 18, 1994 PCT Pub. No. WO94/19364 PCT Pub. Date Sep. 1, 1994The probe comprises: a) an oligonucleotide or oligodeoxyribonucleotide part constituted by a DNA or RNA nucleic acid sequence S, depending on the type of molecule to be detected, and b) a non-nucleotide part possessing chemical properties enabling direct or indirect atttachment of one or more detection units or marking elements M detectable non-isotopically by production of colour or light. The probe is characterized by the fact that part b) is constituted by a chain of phosphate units interspersed with alkyl groups, viz.: b1) certain alkyl groups uniting the different phosphate groups and presenting no special functionality b2) alkyl groups presenting primary amine groups which allow splicing with varied reagents to carry out direct or indirect detection, the b2) groups being bonded to part a) or sequence S by way of groups b1). Sequence S is bonded at its 5' and/or 3' extremity to one or more marking elements M. The probes of this type are used to detect and diagnose hereditary genetic diseases, oncogenes, viral, bacterial or parasitic diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6338105-B1 |
| priorityDate | 1993-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.