| abstract |
PCT No. PCT/GB93/02661 Sec. 371 Date May 24, 1995 Sec. 102(e) Date May 24, 1995 PCT Filed Dec. 24, 1993 PCT Pub. No. WO94/15928 PCT Pub. Date Jul. 21, 1994Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, R and R3 are hydrogen or lower alkyl or R3 is spirocycloalkyl, R1 and R2 are aryl or heteroaryl radicals and n is 1 or 2 and m is 1 to 3 and the total of n+m is 2-4. <IMAGE> (I) |