http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0676410-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e019980e0d3964666d42b84f16f7fe2a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 |
| filingDate | 1995-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1997-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef45db84848cda2b99c412d2b0285ed9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd2fbf20d618bf2af5dcffa6652ec302 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9f271b6ae4e5179edfcd4b2f45ffc5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ddaaceab0e85c2d5e4784930741dc2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10ab9e9dcfef4ecd0ffff4ea9aa36c46 |
| publicationDate | 1997-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0676410-B1 |
| titleOfInvention | Bile acids derivatives useful in the therapy of the biliary calculosis from cholesterol and of the pathologies caused by cholestasis |
| abstract | Amides of the ursodeoxycholic, hyocholic and hyodeoxycholic acids with cyclic aminoacids of general formula <CHEM> and their pharmacologically acceptable organic or inorganic salts. These amides show a metabolic stability, both enteric and hepatic, greater than that of the corresponding bile acids conjugated with glycine or taurine physiologically present in the enterohepatic circulation. The pharmacological activity of the derivatives of formula I and of their pharmacologically acceptable organic or inorganic salts make their use efficacious for the therapy of the biliary calculosis from cholesterol and in every pathology caused by cholestasis like chronic hepatitis from cholestasis, primitive biliary cirrhosis and juvenile hepatopathy joined to cystic fibrosis. |
| priorityDate | 1994-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 138.