| abstract |
Compounds of formula I <IMAGE> formula I where R1, R2, R3, R4, R5, R6, n, and +Z are as defined herein, their use as antiinflammatory, immunosuppressive, and antiallergic agents, pharmaceutical compositions comprising them, and methods for their preparation comprising irradiating compounds of formula II <IMAGE> formula II under an inert atmosphere, in the presence or absence of a compound of formula R3-S-S(O)m-R8, where R7, R8, and m are as defined herein, and methods for their preparation comprising oxidizing, reducing, halogenating, or alkylating compounds of formula I are disclosed. |