http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0672905-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c263ca77673fe333c148a66a2a4680d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-367 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 1995-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99685dd21acde948d058c9962ff86532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3072aac7436598c2d7067e9cc148ef5 |
| publicationDate | 1995-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0672905-A1 |
| titleOfInvention | Induction of the acrosome reaction to evaluate the fertilization capability of mammalian sperm |
| abstract | Disclosed is a method of evaluating the in vitro or in vivo fertilization capability of a given sperm sample. The method involves the steps of capacitating a sample of mammalian sperm cells followed by incubating the capacitated sperm with a predetermined amount of a glycoside-macromolecule conjugate such as a neoglycoprotein or a glycodendrimer for a period of time and under conditions sufficient to induce an acrosome reaction in the sperm. This step effectively mimics the physiological reaction that occurs in vivo between a sperm and an egg. The extent of the conjugate-induced acrosome reaction in the sperm cells relative to a positive control and a negative control, which account for the percent of sperm in the sample that acrosome react non-physiologically and spontaneously, respectively, is then calculated. The fertilization capability of the sperm is then evaluated as a function of the extent of this calculation. Also disclosed are kits which contain the necessary materials for conducting the method in a clinical laboratory. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111044435-A |
| priorityDate | 1994-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.