http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0672684-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_602976225d5368d125cca88df8e61c21 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-53 |
filingDate | 1991-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae92702d2ef5356a645733a7c0c11230 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eacc2cea1f1d6e98a95a8b9335dc6e1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38c0f824e2fcdad90e960efd0097cf2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6bd7515a9bcbd0aa9b6586199f8f1cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf1e3bc64ec2d7f5b39a3d1636f59cdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b08c60cb96acd4638ff4f5ba5d6a886a |
publicationDate | 1995-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0672684-A1 |
titleOfInvention | Novel megakaryocyte colony stimulating factor and production thereof |
abstract | A homogeneous megakaryocyte colony stimulating factor (Meg-CSF) comprising a protein having an activity of forming a megakaryocyte colony from human or mouse myelloid cells in vitro and an activity of increasing the numbers of megakaryocyte precursor cells and megakaryocytes in vivo, said Meg-CSF being produced by culturing cell strains of a large human-derived pulmonary cell carcinoma, e.g. PC-13 strains, or human pulmonary carcinoma cell strains, i.e. MC-1 strains, separated as monoclonal cells from the PC-13 strains, recovering the supernatant of the resulting culture medium, separating the Meg-CSF from the supernatant, and purifying it by a newly developed purification technique. The obtained homogeneous Meg-CSF is a homogeneous protein having a molecular weight of about 23,000 according to gel filtration or about 20,000 according to SDS-PAGE and an isoelectric point of 4.5 to 5.5. The partial amino acid sequence of the protein has been determined. The homogeneous Meg-CSF is useful for treating a certain kind of thrombocytopenia. |
priorityDate | 1990-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 740.