| abstract |
The present patent application discloses compounds having the formulan n or a pharmaceutically acceptable salt thereof nwherein none R²¹ and R²² is alkyl and the other is hydrogen or both of R²¹ and R²² are hydrogen; nand nR¹, R², R³, R⁴, R¹¹, R¹², R¹³, and R¹⁴ each independently are hydrogen, halogen, CF₃, CN, or NO₂; provided that at least one of R¹, R², R³, R⁴, R¹¹, R¹², R¹³, and R¹⁴ are different from hydrogen n The compounds are useful as in vivo active glutamate antagonists. |