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filingDate 1993-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fffdc2c577d00fec97927da5e069b4d
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publicationDate 1997-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0662516-A4
titleOfInvention NEW ELAFINE DERIVATIVE.
abstract A novel elafin derivative having the amino acid sequence represented by formula (I): Ala-Gln-Glu-Pro-Val-Lys-Gly-Pro-Val-Ser-Thr-Lys-Pro-Gly-Ser-Cys-Pro-Ile-Ile-Leu-Ile-Arg-Cys-Ala- X -Leu-Asn-Pro-Pro-Asn-Arg-Cys-Leu-Lys-Asp-Thr-Asp-Cys-Pro-Gly-Ile-Lys-Lys-Cys-Cys-Glu-Gly-Ser-Cys-Gly-Met-Ala-Cys-Phe-Val-Pro-Gln or other amino acid sequence homologous thereto, wherein X represents leucine, isoleucine or valine. This derivative has an oxidation stability superior to that of natural elafin and hence can be utilized as a medicine such as an elastase inhibitor.
priorityDate 1992-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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