| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78032a254510c0569600bda5693dc811 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-44 |
| filingDate |
1994-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abf055dc833c5c84f0f3151c5d57eaa8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e49fe1a7afa6046e639861e569f73f7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95864416a45f92486eec9eb6fc0d7352
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ee8466c49d45121ef1b40375463f41f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d26cd58ffe0ab36491f9e0e259da477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba1af07985e378912094de390ffc97a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d83e7c6d482f39bcf14a5f6dc04ff3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be6c179c9115005446f0663cc7bf7600 |
| publicationDate |
1995-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0658537-A1 |
| titleOfInvention |
Method of producing cis-1-aminoindan-2-ol |
| abstract |
1,2-di-substituted indan expressed by general formula (I) wherein X is a substituent which can be drawn out under an acidic condition to form a carbocation at 1-position of an indan skeleton, Y is a halogen atom, and X and Y can be in either cis - or trans -configuration forming either a racemic body or an optically active substance; or 1,2-di-substituted indan expressed by general formula (I') wherein X is a substituent which can be drawn out under an acidic condition to form a carbocation at 1-position of an indan skeleton, and X and OH group can be in either cis - or trans -configuration forming either a racemic body or an optically-active substance; or cis -1,2-epoxyindan expressed by general formula (VI) wherein R is phenyl or a lower alkyl group is reacted, under an acidic condition, with a nitrile expressed by general formula (II) wherein R is phenyl or a lower alkyl group to form a cis-oxazoline derivative of formula IV wherein R is phenyl or a lower alkyl group and the oxazoline ring is in cis -configuration forming either a racemic body or an optically active substance which is hydrolysed to produce cis -1-aminoindan-2-ol expressed by general formula (V) wherein NHâ‚‚ and OH groups are in c is- configuration forming either a racemic body or an optically-active substance. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BE-1009427-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5841000-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9700237-A1 |
| priorityDate |
1993-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |