Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7235781cfce7bf0621afe9c295b11e0b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-40 |
filingDate |
1994-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f4724e6bf0b01f48e5eef08bbedbb46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39e7a1c174d322215f5892e03253f308 |
publicationDate |
2001-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0656890-B1 |
titleOfInvention |
Novel method for preparing ergothioneine |
abstract |
A method for chemically synthesising the various optical forms of ergothioneine, essentially comprising the steps of preparing or using an optionally optically active Nα,Nα-dimethylated histidine ester salt; treating this compound with an aryl, alkenyl or alkyl halogenothionoformiate in the presence of a base; protecting the sulphur substituent of the resulting compound and converting said compound into a compound such as trimethylammonium; and releasing the desired ergothioneine by saponification or acid hydrolysis as appropriate. An improved yield and an excellent optical purity may thus be achieved. |
priorityDate |
1993-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |