Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7aaf778740331bef568b887e5bdad4f7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 |
filingDate |
1994-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcaaef135b24e4c4bee671f721ebbf98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84b1285371d72e1e1de02dcbf480be05 |
publicationDate |
1995-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0656890-A1 |
titleOfInvention |
Novel method for preparing ergothioneine |
abstract |
A method for chemically synthesising the various optical forms of ergothioneine, essentially comprising the steps of preparing or using an optionally optically active N alpha ,N alpha -dimethylated histidine ester salt; treating this compound with an aryl, alkenyl or alkyl halogenothionoformiate in the presence of a base; protecting the sulphur substituent of the resulting compound and converting said compound into a compound such as trimethylammonium; and releasing the desired ergothioneine by saponification or acid hydrolysis as appropriate. An improved yield and an excellent optical purity may thus be achieved. |
priorityDate |
1993-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |