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filingDate 1993-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d6f2445c544e24ea79915d664de2ee2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2cac067cff6b8292e06d251c6017274
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publicationDate 1995-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0656779-A4
titleOfInvention EMULSIONS IN THE SUBMICRON AREA AS A VEHICLE FOR DRUG ADMINISTRATION ON THE EYE.
abstract An ocular drug delivery vehicle of an oil-in-water submicron emulsion comprising about 0.5 to 50% of a first component of an oil, about 0.1 to 10% of a second component of an emulsifier, about 0.05 to 5% of a non-ionic surfactant and an aqueous component, with the mean droplet size being in the submicron range, i.e., below about 0.5 mu m and preferably between about 0.1 and 0.3 mu m. Also, topical pharmaceutical compositions containing a drug such as an anti-glaucoma drug, beta adrenergic blocker or other autonomic system drug, a local anesthetic, a steroid, a non-steroidal anti-inflammatory drug, an antibiotic drug, an antifungal drug, an antiviral drug or combinations thereof and the vehicle described above. Methods of administering such vehicles or compositions to the eye of a patient while reducing irritation thereof and providing increased bioavailability of the drug.
priorityDate 1992-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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