| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d779448e816f508915ebf0e60c0ba809 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 |
| filingDate |
1993-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bbb9df48c8b8c5dbada921ba99cff89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39b106781eb358c7c37c0fb9f0012c5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a744ed4d50950c245fa3f8ab5fa17f19 |
| publicationDate |
1995-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0654993-A1 |
| titleOfInvention |
Method for destroying or inhibiting growth of unwanted cells or tissues |
| abstract |
This invention is a process for the use of a combination of ionizing radiation in conjunction with certain benzoporphyrin derivative compounds (BPD), preferably the compound benzoporphyrin derivative - monoacid ring-A (BPD-MA), to mediate the destruction of diseased or unwanted cells or tissues. Specifically, the invention is a method in which the sensitizer compounds are administered either systemically or locally to the diseased or unwanted tissue and irradiated with ionizing radiation (such as might be produced by a 60Co or x-ray source). The treatment with benzoporphyrin derivative compounds appears to sensitize the target cells or tissues in that those cells do not readily recover from irradiation exposure. In addition, the process may be used to lower the effective amount of radiation applied to a particular tissue target. |
| priorityDate |
1992-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |