abstract |
A method of treating resistant neoplasms comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula <CHEM> wherein R<1> and R<3> are independently hydrogen, -CH3, <CHEM> or <CHEM> wherein Ar is optionally substituted phenyl; R<2> is selected from the group consisting of pyrrolidino, hexamethyleneimino, and piperidino, a pharmaceutically acceptable salt or solvate thereof. |