abstract |
Methods of inhibiting smooth muscle cell proliferation and restinosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula <CHEM> or <CHEM> wherein R1 and R3 are independently hydrogen, -CH3, <CHEM> or <CHEM> wherein Ar is optionally substituted phenyl; R2 is <CHEM> and R4 is hydrogen or -OR1, and pharmaceutically acceptable salts and solvates thereof. Also provided is a method for inhibiting restinosis. |