| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50bce2157aca61ab9bf34ed7d89717cc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-22 |
| filingDate |
1993-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_677bd6dc0fb86a9e6535657451741a9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6df98a496302508afe2d9f68bb27bdbd |
| publicationDate |
1998-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0651736-B1 |
| titleOfInvention |
PROCESS FOR PREPARING ENANTIOMER-PURE beta-SUBSTITUTED gamma-AMINOBUTYRIC ACID DERIVATES, NEW ENANTIOMER-PURE INTERMEDIATE STAGES OF SAID PROCESS AND THEIR USE |
| abstract |
A process is disclosed for preparing enantiomer-pure (beta)-substituted (gamma)-aminobutyric acid derivates and related compounds. A S-pyroglutaminic acid derivate having general formula (II), in which Y stands for a sterically demanding OH-protecting group known per se, is reacted with an organometallic reactive which allows a residue R to be selectively introduced into the 4th position adjacent to the -CH2OY group of the compound having general formula (II). A compound having general formula (III) is thus obtained, from which a series of pharmaceutically interesting compounds may be derived, such as R-baclofen and R-rolipram, while preserving the stereochemical properties of the substituents. |
| priorityDate |
1992-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |