http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0648130-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcff13f8573db698307f919e6385d5c4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-14 |
| filingDate | 1991-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3c4f69e9baad0a672a1fa455f839ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c437cb2cee10d6ab4767f004d4f44c5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cd07f4e890b4ea16bf02738bcf19e0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c996a42badaa0ae33db1195f07f7cc1 |
| publicationDate | 1998-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0648130-B1 |
| titleOfInvention | Radioiodinated benzovesamicol analogs for cholinergic nerve mapping |
| abstract | Radioiodinated benzovesamicol analogs which selectively localize in presynaptic cholinergic neurons of the general formula: <IMAGE> where X is selected from the group consisting of H, OH, NH2, NHCO-3-[I]-Ph, and a radioactive isotope of iodine, and Y is selected from the group of H and a radioactive isotope of iodine, Y being H is X contains iodine. Illustrative examples include: (+/-)-trans-2-hydroxy-5-iodo-3-(4-phenylpiperidino)tetralin; (+/-)-trans-3-hydroxy-5-iodo-2-(4-phenylpiperidino)tetralin; (+/-)-trans-5-amino-2-hydroxy-8-iodo-3-(4-phenylpiperidino)tetralin; and (+/-)-trans-2-hydroxy-5-(3-iodobenzamido)-3-(4-phenylpiperidino)tetralin. The novel radioiodinated benzovesamicol analogs may be used as radiopharmaceuticals to visualize cholinergic neurons with conventional imaging devices which are typically found in most nuclear medicine or radiology clinics. |
| priorityDate | 1990-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 190.