http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0644775-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f4246e8fcebf17c365aced017a04c61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b3c81bc92f0f06434ec1a01cd0137ab |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D253-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
filingDate | 1992-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ecdd55887add76128c50e56ced50d70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2523b2b20c98e737a8c435d1f5d4c62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_747a13bfbfe93176ebd4477c2e41162a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab022366c70183173eb0eda6bde8081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe5a04a42fa97d00e1ea01c2ffdf5ca |
publicationDate | 1999-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0644775-B1 |
titleOfInvention | Cocaine Receptor Binding Ligands |
abstract | Novel compounds show high affinity for specific cocaine receptors in the brain, particularly dopamine transporter sites, and have the formula Wherein Y = CH<sub>2</sub>R<sub>3</sub>, CO<sub>2</sub>R<sub>2</sub> orR<sub>1</sub> =hydrogen, C<sub>1-5</sub> alkyl,R<sub>2</sub> =hydrogen, C<sub>1-6</sub> alkyl, C<sub>3-8</sub> cycloalkyl, C<sub>1-4</sub> alkoxy, C<sub>1-6</sub> alkynyl, halogen or amine,R<sub>3</sub> =OH, hydrogen, C<sub>1-6</sub> alkyl, C<sub>3-8</sub> cycloalkyl, C<sub>1-4</sub> alkoxy, Cl, Br, I, CN, NH<sub>2</sub>, NHC<sub>1-6</sub> alkyl, NC<sub>1-6</sub> alkyl, OCOC<sub>1-6</sub> alkyl, OCOC<sub>1-3</sub> alkylaryl,A =S, O or NHX =H, C<sub>1-6</sub> alkyl, C<sub>3-8</sub> cycloalkyl, C<sub>1-4</sub> alkoxy, C<sub>1-6</sub> alkynyl, halogen, amino, acylamido, andZ =H, I, Br, Cl, F, CN, CF<sub>3</sub> NO<sub>2</sub>, N<sub>3</sub>, OR<sub>1</sub>, CO<sub>2</sub>NH<sub>2</sub>, CO<sub>2</sub>R<sub>1</sub>, C<sub>1-6</sub> alkyl, NR<sub>4</sub>R<sub>5</sub>, NHCOR<sub>5</sub>, NHCO<sub>2</sub>R<sub>6</sub>, wherein R<sub>4</sub>-R<sub>6</sub> are each C<sub>1-6</sub> alkyl. |
priorityDate | 1991-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.