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filingDate 1993-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c53bcaa494d8092c244360f791254e91
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publicationDate 1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0643837-B1
titleOfInvention Manufacturing process for sample initiated assay device
abstract The quantitative test device is manufactured by attaching the critical component of a two-component dye system to minute particles such as microcrystalline cellulose, silica, or latex, which particles are suspended in a solution of a polymeric binder. Additional non-immobilized components of the reaction system of the test device are optionally added to the polymer solution. The suspension of dyed particles in polymer solution is applied to a fabric as a coating, using conventional coating machines, to obtain a homogeneous distribution of immobilized dye throughout the fabric. The measurement zone is made from a film support made of a material having a lower melting point than the filter cloth fabric used in the measurement zone was used. By using a lower melting point material for the support film, impulse heat sealing is controlled to a degree such that the lower melting point support is made to melt and extrude through the mesh of the fabric on either side of the channel, forming a seal along the sides of the channel. The device may be manufactured using a feedback loop which allows one to modify continuously the dimensions of a reading scale printed on the device.
priorityDate 1992-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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