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filingDate 1993-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0440b4a261f1050afc3089ca3f96ac36
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publicationDate 1995-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0643726-A1
titleOfInvention PEPTIDES OF HUMAN p53 PROTEIN FOR USE IN HUMAN T CELL RESPONSE INDUCING COMPOSITIONS, AND HUMAN p53 PROTEIN-SPECIFIC CYTOTOXIC T-LYMPHOCYTES
abstract PCT No. PCT/NL93/00102 Sec. 371 Date Feb. 6, 1995 Sec. 102(e) Date Feb. 6, 1995 PCT Filed May 18, 1993 PCT Pub. No. WO93/24525 PCT Pub. Date Dec. 9, 1993A peptide comprising an amino acid sequence derived from human p53 protein, wherein said amino acid sequence has the ability to bind to a human MHC Class I molecule. Its use in prophylactic or therapeutic treatment of diseases such as human cancers showing p53 protein overexpression, and its use in induction of primary p53-specific T cells that can be used in therapeutic treatment. Its use in diagnostic tests or assays.
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