http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0643721-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c81d97576dbeeb2b3e24fb19792da2e1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate | 1991-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7449c352ed5a714febf9db2ebb3a2e09 |
publicationDate | 1995-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0643721-A1 |
titleOfInvention | Method of synthesizing sulfurized oligonucleotide analogs |
abstract | A method for synthesizing sulfurized oligonucleotide analogs, such as phosphorothioate and phosphorodithioate analogs, is provided that employs a thiuram disulfide as a sulfurizing agent. The method of the invention may be used to sulfurize any phosphorous(III)-containing intermediate. Preferably, the method is practiced on a commercial DNA synthesizer using phosphoramidite and/or phosphorthioamidite intermediates. |
priorityDate | 1991-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.