abstract |
Compounds of formula (I) or (II) and pharmaceutically acceptable salts and prodrugs thereof, wherein R1 is C1 to C8 alkyl and Q is selected from (a), (b), (c), (d), (e) and (f), wherein Y is selected from (III), (IV), (V), (VI), (VII), (VIII), (IX) and (X) and Z is selected from groups of formula (XI), with the pharmaceutically acceptable salts and prodrugs of the aforesaid formula I or II final products being derived from the hereinbefore described Y and Z acid groups. These compounds are useful in treating aging skin, and also skin conditions such as psoriasis, acne and related disorder of keratinization and epithelial differentiation, as well as skin tumors. |