| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41686a979f961bce6a9855b4b409a5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-33 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6851 |
| filingDate |
1994-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f537aa6f00c3de5cd441ef582c48308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caf9be3a28dc0c7aa3f46d5984efab65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a79aeda92503cf1f9e84a4afbc23d28a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b53411ad7797e39fdce73eec448f344
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_652c1fb0bdeaa44bf2139a4a7c1cb9aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dae51cd415c12f0e0d56a0ed93bf58ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d363371459ff4a51b1ee3c6d51768997 |
| publicationDate |
1995-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0640691-A2 |
| titleOfInvention |
Detection of mycobacteria by multiplex nucleic acid amplification |
| abstract |
Primers and methods for adapter-mediated multiplex amplification of the IS6110 insertion element of Mycobacterium tuberculosis (M.tb) and the 16S ribosomal gene of Mycobacterium tuberculosis , useful for simultaneously detecting and/or identifying species of the M. tuberculosis complex and other clinically relevant Mycobacterium species. Multiplex Strand Displacement Amplification (SDA) is used in a single amplification reaction which is capable of simultaneously identifying M. tuberculosis and providing a screen for substantially all of the clinically relevant species of Mycobacteria. Also disclosed are methods for adapter-mediated multiplex amplification of multiple target sequences and a single internal control sequence for determination of sample efficacy or quantitation of the targets. In a preferred embodiment, an internal control sequence is included in the amplification reaction and coamplified with the IS6110 and 16S target sequences as an indication of sample amplification activity or to quantitate the initial amount of target sequences in the sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7271781-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7112423-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0725148-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0725148-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9641000-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100455032-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9683255-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8043834-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6884586-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5882857-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0015849-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6255082-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0805213-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0795611-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0805213-A3 |
| priorityDate |
1993-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |