| abstract |
Azepin-(2,1-A) isoquinoline derivs of formula (I) and their salts are new. A = C(O)C(R1)(R12)-(CH2)nSR2, etc.; R1,R12 = H, cycloalkyl, opt. substd. alkyl, etc.; R2 = H, COR6 or SR11; R6 = cycloalkyl(CH2)p, heteroaryl(CH2)p or opt. substd. alkyl or aryl (CH2)p-; R11 = cycloalkyl(CH2)p, heteroaryl(CH2)p, etc.; p = 0-6; R3 = , opt. substd. alkyl or aryl(CH2)p, heteroaryl (CH2)p-, etc.;X1, X2 = H, lower alkyl, lower alkoxy, lower alkylthio, halo, CF3, OH, amino, NH lower alkyl, etc. |