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filingDate 1994-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1995-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0638321-A1
titleOfInvention Ipriflavone and pharmaceutical compositions and their use for bone defect substitution
abstract The invention relates to the use of Ipriflavone (7-isopropoxyisoflavone) and combinations thereof with porous hydroxylapatite and/or tricalcium phosphate for the substitution of bone defects having pathologically developed or being artificially established, as well as to compositions containing these active ingredients and their preparation. n In the combinations of the invention, the mass ratio A/B of porous hydroxylapatite and/or tricalcium phosphate (A) to Ipriflavone (B) is preferably 1:9 to 9:1 and most preferably 1:1. The components are preferably present in the form of discrete granules. n Preferably, the Ipriflavone is applied onto the surface of the porous hydroxylapatite and/or tricalcium phosphate. n The compositions of the invention lead to an accelerated bone formation.
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priorityDate 1993-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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