abstract |
Disclosed is a compound of formula (I) where R1 is H, NH¿2?, or OCH3, R?2¿ is an optionally substituted cyclic group optionally containing one or more heteroatoms, R?3 and R4¿ are independently H or C¿1-4? alkyl, m is 0-4, n is 0-6, p is 0.1, X is CN, CSNH2, PO(OH)2, COOH, SO2NH2, NH2, OH, CNHNH2, tetrazole, triazole, or COR?5¿ where R5 is C¿1-4? alkyl, CF3, NH2, or OC1-4 alkyl, and Y is O or NH that is useful as a pharmaceutical. |