http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0637967-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ee28fc7fdd2b138c0a64cb60c7e0550 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9215c94df510953a87a36f40ae003c9 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 1992-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f0369946124a2944dae135ffe6003d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e1f5259027111a2ad2d20f196833db0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f382e7365ff8dd561668250fd332e8db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2902d5671a65af2b053d78ede04bf489 |
publicationDate | 1995-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0637967-A1 |
titleOfInvention | Improved method |
abstract | The present invention relates to a method for determining the effect of a drug or a treatments, comprising introducing, in a non-human vertebrate recipient which may be an immunodeficient, e.g. a nude mouse, cells from a donor vertebrate, e.g. a human, which mediate the disease, the donor cell or cells of the recipient being modified, e.g. marked with a genetic marker such as lacZ gene, administering the drug or the treatment to the non-human recipient vertebrate, and determining the effect of the drug or the treatment. When the genetic marker is lacZ gene, the detection is performed by staining with the chromogenic substrate X-gal resulting in a blue staining of the labelled cell. In a further aspect, the invention relates to a method for controlling the progression of cancer cells in a human or animal patient, comprising administering to the patient fibroblasts which have been transformed with a genetic construct expressing a gene product inhibiting the progression of cancer cells. |
priorityDate | 1992-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1376.