| abstract |
Compounds of formula (I), and salts and prodrugs thereof wherein: R1 is H, certain optionally substituted C¿1-6?alkyl, or C3-7cycloalkyl; R?2¿ represents a group (a) wherein X is O, S or NR8 where R8 is H or C¿1-4?alkyl; one of Z and Y is C=O and the other is O, S or NR?9¿, where R9 is H or C¿1-4?alkyl; R?3¿ is C¿1-6?alkyl, halo or NR?6R7; R4¿ is C¿3-10?cycloalkyl; n is 0, 1, 2, or 3; are CCK and/or gastrin receptor antagonists. They and compositions thereof are useful in therapy. |