http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0636171-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0aa69135efb653aad3b2a98fa55c0f58 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59 |
filingDate | 1993-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2000-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c30e58cceafd8c29a557b97f5c5f5013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26072ca57d00c5d06ddf78aac8513cd1 |
publicationDate | 2000-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0636171-B1 |
titleOfInvention | Methods of using antibodies against human chorionic gonadotropin-related determinants to lyse malignant cells |
abstract | The invention provides a method of lysing malignant cells, which comprises contacting the malignant cells with an antibody which specifically reacts with an epitope present on the beta subunit of human chorionic gonadotropin and/or beta subunit fragment, under conditions such that the malignant cells lyse. This invention further provides a method of quantitatively measuring malignant cells or a method of obtaining an enriched population of malignant cells, which comprises contacting live malignant cells to be measured or contacting a population of cells comprising live malignant cells with an antibody directed to an epitope of human chorionic gonadotropin, its subunits and/or subunit fragments, under conditions such that the antibody is capable of forming a complex with the epitope if present on the cell surface, and detecting the presence of any complex formed using fluorescence activated cell sorting technology, the presence of such complex on the surface of the cells indicating that the cells are malignant, and isolating the cells which form a complex with the antibody. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014159813-A1 |
priorityDate | 1992-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.