abstract |
Novel 4-aryloxy- or 4-arylthiopiperidine derivatives of the formula I <IMAGE> in which R<1> and R<2> in each case independently of one another are phenyl radicals which are unsubstituted or substituted one or two times by A, OH, OA, aryloxy having 6-10 C atoms, aralkyloxy having 7-11 C atoms, -O-(CH2)n-O-, Hal, CF3, NO2, NH2, NHA, NA2, NHAc, NAAc, NHSO2A and/or NASO2A, X is O, S, SO or SO2, m is 1, 2 or 3, n is 1 or 2, A is an alkyl radical having 1-6 C atoms, Hal is F, Cl, Br or I and Ac is alkanoyl having 1-8 C atoms, aralkanoyl having 1-10 C atoms or aroyl having 7-11 C atoms, and their physiologically acceptable salts, have an action affecting the central nervous system, in particular neuroleptic action, without a noticeable cataleptic action occurring. |