| abstract |
Novel compounds represented by the formula:n n wherein the ring A and the ring B each stand for an optionally substituted benzene ring; nAr stands for an optionally substituted aryl group or an optionally substituted heterocyclic group; nQ stands for an oxygen atom or a sulfur atom; nR stands for a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted hydroxyl group or an optionally substituted amino group; nX stands for -O- or -NR¹- wherein R¹ stands for a hydrogen atom or an optionally substituted hydrocarbon group; nY stands for -O-, -NR²- wherein R² stands for a hydrogen atom or an optionally substituted hydrocarbon group, or a bond; nm denotes 1, 2 or 3, and nn denotes 0, 1 or 2, and salts thereof which have an excellent calcium- or substance P receptor-antagonistic activity, being useful for treating a cerebralvascular disorder in mammals such as cerebralischemia, cerebral edema and neuronal damage, their production and use. |