abstract |
The invention relates to 1-alkoxy-2- (alkoxy- or cycloalkylosy) -4- (cyclothioalkyl- or cyclothioalcenyl-) benzene compounds which inhibit cyclic AMP phosphodiesterase or tumor necrosis factor (FNT) and which are useful in treating patients with medical conditions which may be modulated by inhibiting the production of cyclic AMP phosphodiesterase or FNT by administering the compound to patients. The invention also relates to the preparation of these compounds, the pharmaceutical compositions containing these compounds and the methods of their pharmaceutical application. |