| abstract |
Novel tetralin derivatives having inhibitory activity against 3-hydroxy-3-methylglutaryl-coenzyme A reductase, represented by the general formula (I) wherein R1 is hydrogen or acetyl, R2 is carboxy and R3 is hydroxy, or R2 and R3 may form a lactone, and pharmaceutically acceptable salts. The invention also relates to methods for producing these compounds, as well as to a pharmaceutical composition containing them. |