http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0623680-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
| filingDate | 1994-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300ab8885160f09c8dbbda847c1e1ec2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_370429006b8a062f824dd2dc666ba9e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c1db1c79eaaf0f0fdaf631e0dd03bb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_831502f57fce6d8edcc9795f82d773df |
| publicationDate | 1994-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0623680-A1 |
| titleOfInvention | Process to synthesize peptides and its use |
| abstract | 2.1. The enzymatic synthesis of peptides is advantageously achieved by means of proteases, but the hydrolysis of the acylenzyme intermediate associated with the formation of the peptide product and further possible proteolytic cleavages pose a problem in many synthesis reactions. As a result, the yield of peptide product remains limited and the separation of by-products is difficult. The new biocatalytic peptide production should take place with the greatest possible exclusion of undesirable proteolytic side reactions.n n n 2.2. The biocatalytic production of a peptide is advantageous if a zymogen is used instead of the protease that is usually used. Since zymogens are proteolytically still inactive precursors of proteases, proteolytic side reactions are largely suppressed. Amino acid esters or peptide esters and C-terminally derivatized amino acids or peptide fragments are preferably coupled to one another. The reaction can also take place in a frozen aqueous medium. Chymotrypsinogen, trypsinogen, pepsinogen, prorennin or pro-carboxypeptidase are particularly suitable as zymogens.n n n 2.3. Enzymatic or biocatalyzed peptide synthesis. |
| priorityDate | 1993-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.