abstract |
The subject of the invention is the compounds of formula (I) in which R17 and R'17 are such that: either R17 and R'17 together form a ketone, hydrazono, oxime, methylene; either R17 is hydroxyl, hydroxymethyl, acyloxy and R'17 represents hydrogen, alkyl, alkenyl or alkynyl optionally substituted; R3 is hydrogen, alkyl; R16 is hydrogen, halogen, alkyl; m has the value 0, 1 or 2; X, Y and Z are such that: X represents methylene, arylene or arylenoxy linked to the steroid by a carbon atom; Y represents a linear or branched, saturated or unsaturated aliphatic chain optionally interrupted by oxygen, Z represents a linear or branched alkyl, or an aryl or arylalkyl, and the addition salts thereof, their preparation, their use as medicaments, the compositions containing them and the new intermediates obtained. |