abstract |
Benzopyran and other benzo-fused leukotriene B4 antagonists have formula (I) wherein A, n, R?1, R2 and R3¿ are as defined herein. The compounds of formula (I) wherein R1 is c-substituted CR?4R5-COOR13¿ may be prepared from the corresponding c-substituted CF¿3?SO3 compound by reaction with a trimethylsilyl ketene acetal. |