http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0621779-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d3f592d2421c1ac365bf3a62e76e490 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20da8545546069b0cef3c88ca9843960 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-405 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-26 |
filingDate | 1993-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b3d14bda479043ef77786aea7a10c09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f82886f52cbb8731c0554be90ac90161 |
publicationDate | 2005-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0621779-B1 |
titleOfInvention | Indomethacin lysinate for therapeutic use in ophthalmology |
abstract | Use of an arylacetic, arylpropionic or arylbutanoic compound, of a benzoic or nicotinic acid derived compound for the production of a sterile drug for use in ophtalmological therapy, wherein the compound penetrates into the eye tissues and humours, and/or in otorhinolaryngological therapy in the form of an isotonic aqueous solution with neutral pH or with a pH in the region of neutrality, or in the form of a suspension, a gel or an emulsion containing other ions. The compound is present in the solution, suspension, gel or emulsion as the only active ingredient in the form of an isolated salt in a pure form and is devoid of any residual solvent except, possibly, traces of ethanol. The invention also relates to the production of said salt isolated in a pure form, characterized in that it consists in reacting the carboxylic function with the amine function in a hydro-ethanolic medium without any other organic solvent resulting in a final product devoid of any other residual solvent other than ethanol. |
priorityDate | 1992-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.