| abstract |
The invention relates to novel thiosemicarbazonethiones of the formula (I). In this formula, R1 is lower alkyl, lower alk-2-ene-1-yl or also lower alk-2-yn-1-yl, R2 and R3 each independently represent hydrogen, or lower alkyl, or together they form lower alkylidene, R4 is hydrogen, lower alkyl, lower alkoxy, aryl or lower arylalkyl, R5 is lower alkyl, aryl, lower arylalkyl, lower unsaturated heterocyclylalkyl or saturated or alternatively a lower alkyloxycarbonylalkyl. The invention also relates to the salts of these compounds, to a process for the preparation of these compounds, to the pharmaceutical compositions containing them, and to their use as medicaments. |