http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0617006-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d0a8ea672d066d4370308d83f2e66ab |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 1994-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2e49723867a3de12c07909c8e234a5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cb9b38d686754ced66fc5e7ccfe2583 |
| publicationDate | 1994-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0617006-A1 |
| titleOfInvention | N-subtituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation |
| abstract | The invention provides the preparation procedure for N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine having the general formula ( I ), where R is hydrogen, benzyl and p-nitrobenzyl group, and n is 0 , and where R is aryl, alkylaril and alkyl group with C₁ to C₄ atoms, and n is 1 , and also covers the compounds of the general formula ( I ), where R is aryl and alkylaril group, and n is 0 and 1 .n n According to this invention by condensation of N-substituted derivatives of N-methyl-3-phenyl-3-hydroxypropylamine ( XV ), where R is benzyl and p-nitrobenzyl group and n is 0 , and p-trifluoromethylchlorbenzene ( XVI ) prepared are N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine ( I ), where n and R are the same as in the compound ( XV ), which by the reaction with chloroformic acid esther ( XVII ), where R is aryl, alkylaril and alkyl group with C₁ to C₄ atoms, are converted to N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine ( I ), where R is the same as in the compound ( XVII ), and n is 1 , from which N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine ( I ) is prepared by basic hydrolysis and/or catalytic hydrogenolysis, when R is benzyl and p-nitrobenzyl group, and n is 0 and 1 . |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9811054-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011145102-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5936124-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2120368-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6025517-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6028224-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0007976-A1 |
| priorityDate | 1993-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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