http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0615445-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5d8a3b3b3faac2562bcdcd68af92186 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-906 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-915 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G03C2001-0471 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 1992-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1996-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6fde691f9a5f63e7e1b0aff6ffb81f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b06538195f2fcb38c87b3ef4a664e558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3006cfeed40c30057369ecd20a975620 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf6687b4aee1c4fdcaf2e92363bbe82a |
| publicationDate | 1996-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0615445-B1 |
| titleOfInvention | Pharmaceutically applicable nanosol and process for preparing the same |
| abstract | PCT No. PCT/DE92/01010 Sec. 371 Date Oct. 25, 1994 Sec. 102(e) Date Oct. 25, 1994 PCT Filed Dec. 4, 1992 PCT Pub. No. WO93/10768 PCT Pub. Date Jun. 10, 1993Nanosols and process for preparing the same allow colloidally dispersed solutions of scarcely water-soluble active substances to be stabilized with gelatin or its derivatives, by partly or fully setting the iso-ionic point (IIP, equivalent to a neutral charge) between the gelatin and the surface charged active substance particles. In order to neutralize the charge of the system composed of active substance particles and gelatin, the surface charge of the particles is compensated by a corresponding opposite charge of the gelatin molecules. For that purpose, a determined charge in relation to the isoelectric point (IEP) and the pH value of the solution is set on the gelatin molecules. By stabilizing in this way the practically monodispersed state thus generated, the Ostwald maturation of the colloidal particles of scarcely soluble active substance is strongly reduced. A new form of pharmaceutical administration having new properties can thus be obtained with generally scarcely water-soluble inorganic and organic compounds, in particular medicaments with a problematic bioavailablity. Preferred medicaments are glibenclamide and 3-indolylacetic acid derivatives, such as indomethacin or acemetacin. |
| priorityDate | 1991-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 288.