http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0613470-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b58f981963f6d55d627139e778c4ef7b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 |
| filingDate | 1992-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1996-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c5fcf8441be0761fb3feb6fbc97c4a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_040546efa6f5fd7080feb948f34fdcf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8248683a612b6c5e26202a3ff954cae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3451c20f342bfe5e060672da94b028e3 |
| publicationDate | 1996-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0613470-B1 |
| titleOfInvention | Novel 4-cinnolinone derivatives, their preparation and application in therapy |
| abstract | Novel 4-cinnolinones of general formula (I) in which: A denotes oxygen or an NR3? grouping; R1? denotes: hydrogen, a C1-4? alkyl radical, a C1-4? phenyl alkyl radical or an aminoalkyl grouping; R2? is: a C2-5? alkyl, C3-5? alkenyl, C2-5? hydroxyalkyl, C1-3? alcoxy, C1-4? alkyl radical, a phenyl radical or a C1-3? phenyl alkyl radical; X denotes one or more groupings such as hydrogen, halogen, C1-3? alkyloxy, trifluoromethyl. The invention also concerns the process for their preparation and pharmaceutical compositions comprising as active principle at least one of the compounds of formula (I). R1? denotes: hydrogen or a C1-4? alkyl radical, a C1-4? phenyl alkyl radical, where the aromatic nucleus can be substituted by one or more groupings such as halogen, C1-3? alkyl, C1-3? alkyloxy, trifluoromethyl, an aminoalkyl grouping (II) in which n stands for an integer between 1 and 4 inclusive and R4?, R5?, the same or different, denote hydrogen, a C1-3? alkyl radical or together form with the nitrogen atom to which they are bound a heterocycle such as pyrrolidine, piperidine, morpholine or piperazine. R2? denotes: a C2-5? alkyl, C3-5? alkenyl, C2-5? hydroxyalkyl, C1-3? alcoxy, C1-4? alkyl radical, a phenyl radical or a C1-3? alkyl phenyl, where the aromatic nucleus can be substituted by one or more groupings such as halogen, C1-3? alkyl, C1-3? alkyloxy, trifluoromethyl. X denotes one or more groupings such as hydrogen, halogen, C1-3? alkyl, C1-3? alkyloxy, trifluoromethyl. The invention also relates to pharmaceutical compositions comprising as active principle at least one of the compounds of formula (I). |
| priorityDate | 1991-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.