| abstract |
Compounds of formula (I), in which A represents C = C, S or O; Q represents a pentagonal or hexagonal unsaturated heterocyclic compound having a nitrogen atom which is in a position adjacent to the bond point, 0 to 3 other heteroatoms selected from N, O and S, and substituents R6 and R7; R1 represents H or C1-6 alkyl; R2 represents H, C1-6 alkyl, C3-6 alkenyl, C3-6 alkynyl, C3-6 cycloalkyl or NH2CH2CO-; further R1 and R2 taken together can form a C3-5 alkylene chain; R3 represents H, C1-6 alkyl, C3-6 alkenyl, C3-6 alkynyl; R4 and R5 independently represent H, OH, C1-6 alkoxy, C1-6 alkyl, halogen, trifluoromethyl or NR8R9; R6 and R7 independently represent H, OH, C1-6 alkoxy, C1-6 alkyl, halogen, trifluoromethyl, C1-6 hydroxyalkyl, amidino, CONH2 or NR8R9; in addition R6 and R7 can independently represent O in the event of substitution for N; R8 and R9 independently represent H or C1-6 alkyl; with several conditions. The invention also relates to pharmaceutically acceptable derivatives of these compounds; said compounds being useful as pharmaceuticals for treating neurological disorders. |