http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0611368-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 1992-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1fc4fce1de49a1dbf55c9d99f34c028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb7017e6d7927bf764c1ed2fca57c4ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58791880a36e73716f3204fafd62e3ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45df23b8f559202bb1985864d76e5353 |
| publicationDate | 1994-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0611368-A1 |
| titleOfInvention | SUBSTITUTED AMINOPYRIMIDINE AS ANGIOTENSIN II ANTAGONISTS. |
| abstract | The invention relates to compounds of formula (I) wherein R1 represents alkyl having 1 to 6 carbon atoms, perfluoroalkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, fluoro, chloro, or bromo; R2 represents hydrogen, alkyl having 1 to 6 carbon atoms, perfluoroalkyl having 1 to 6 carbon atoms, trifluoromethylalkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, alkoxy having 1 to 6 carbon atoms, hydroxy , fluoro, chloro, bromo or cyano; R3 represents hydrogen, perfluoroalkyl having 1 to 6 carbon atoms, trifluoromethylalkyl having 1 to 6 carbon atoms, alkyl having 1 to 6 carbon atoms, alkenyl having 3 to 5 carbon atoms, alkynyl having 3 to 5 carbon atoms, aryl having 6 to 10 carbon atoms, aryl having 6 to 10 carbon atoms substituted by fluorine, chlorine or bromine; aralkyl having 7 to 12 carbon atoms; aralkyl having 7 to 12 carbon atoms and substituted by alkyl having 1 to 6 carbon atoms, fluorine, chlorine or bromine; alkoxy having 1 to 6 carbon atoms or alkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, pyridylmethyl, thienylmethyl, fluoro, chloro, bromo, cyano, hydroxyalkyl having 1 to 6 carbon atoms, (CH2 ) mCO2R5, (CH2) mCONR5R6, or else represents, taken with R2, a methylene chain having 2 or 3 carbon atoms; m can be from 1 to 4; n can be from 0 to 3; R4 represents hydrogen, alkyl having 1 to 6 carbon atoms, aryl having 6 to 10 carbon atoms, aryl having 6 to 10 carbon atoms substituted by halogen, alkylcarbonyl having 2 to 6 carbon atoms, pyridyl, or pyrimidinyl; R5 and R6 represent H or alkyl having 1 to 6 carbon atoms; Ar1 represents (a), (b) or (c); Ar2 represents (d), (e), (f) or (g) where X represents CO2H, CO2R7, NHSO2CF3 or else (h) where R7 represents hydrogen, alkyl having 1 to 6 carbon atoms, benzyl, triphenylmethyl, or Sn (alkyl having 1 to 6 carbon atoms) 3. The invention also relates to the pharmaceutical salts |
| priorityDate | 1991-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 306.