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filingDate 1992-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fbade3e690f6a2f20d884ade7a7f4c6
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publicationDate 1994-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0608306-A1
titleOfInvention PERORAL DISPOSAL SYSTEM.
abstract Device allowing the peroral administration of a therapeutic agent which may exist in a non-ionized and therapeutically active form. The device comprises a reservoir comprising the therapeutic agent in ionized form, and having a wall permeable to non-ionized materials but impermeable to ionized materials. It also comprises a solid material capable of becoming a buffer when it absorbs water, and having, during this absorption, a pH determining the rate of infiltration through the wall of the reservoir of the therapeutic agent in the form non-ionized. This device allows the delivery of the therapeutic agent to be regulated by the pH of the buffer and possibly by the composition of the walls of the reservoir. The composition of the surrounding aqueous medium has no influence on the rate of administration.
priorityDate 1991-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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