http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0607795-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20 |
| filingDate | 1994-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c642274387a2598e555597610cd69c60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71cfe1dbf1b25193e9631db99d359f3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737abbebce6a2d6b65f09997f6d93130 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8605dfcc48c8e6a4baa462a55b30582 |
| publicationDate | 1994-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0607795-A1 |
| titleOfInvention | Process for the preparation of 2-alkyl-4-fluoromethyl-thiazole-carboxylic acid esters |
| abstract | R¹ Alkyl R² Difluormethyl oder Trifluormethyl und R³ Alkyl bedeuten, nindem man Carbonsäurethioamide der Formel IIn n in welcher R¹ die oben angegebene Bedeutung hat, mit 2-Chlor-4-fluoracetessigsäurealkylestern der Formel IIIn n in der R² und R³ die oben angegebenen Bedeutungen haben, in einem aprotischen Lösungsmittel bei Temperaturen unter 100°C zur Reaktion bringt und mit einem wasserabspaltenden Mittel, gegebenenfalls in Gegenwart von Basen, bei Temperaturen unter 80°C umsetzt.Process for the preparation of 2-alkyl-4-fluoromethylthiazolecarboxylic acid alkyl esters of the formula I. in which R¹ Alkyl R² Difluoromethyl or trifluoromethyl and R³ Alkyl mean, by using carboxylic acid thioamides of the formula II in which R¹ has the meaning given above, with 2-chloro-4-fluoroacetoacetic acid alkyl esters of the formula III in which R² and R³ have the meanings given above, reacting in an aprotic solvent at temperatures below 100 ° C. and reacting with a water-releasing agent, optionally in the presence of bases, at temperatures below 80 ° C. |
| priorityDate | 1993-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.