| abstract |
Aryl-fused- and hetaryl-fused-2,4-diazepines of formula XXXVI,n n wherein n A is an aryl, cycloalkyl or hetaryl or substituted aryl ring n R¹ is hydrogen, alkyl, aralkyl, aryl, hetaryl or substituted aryl; n R² is hydrogen, alkyl, aralkyl, aryl or substituted alkyl or aryl; n R³ is alkyl, aryl, aralkyl, hetaryl or heteroatom substituted alkyl, aryl, aralkyl or hetaryl; n R⁴ is hydrogen, alkyl or substituted alkyl; n R⁵ is hydrogen, alkyl, aryl, aralkyl, hetaryl or substituted aryl, npharmaceutical compositions containing these and methods of treating cardiac arrhythmia with the compounds of formula XXXVI are disclosed. |